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Effect of the Folic Acid Analogue, Trimethoprim, on Growth, Macromolecular Synthesis, and Incorporation of Exogenous Thymine in Escherichia coli
The effect of trimethoprim [2,4-diamino-5(2′,4′,5′trimethoxybenzyl)-pyrimidine] in the presence of thymine on Escherichia coli B temperature-sensitive and non-temperature-sensitive Thy(′) strains and a phosphodeoxyribomutase-negative mutant was studied. The inhibitory effect of 5 μg of trimethoprim...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1972
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC247509/ https://ncbi.nlm.nih.gov/pubmed/4260561 |
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