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Nucleotide excision repair deficient mouse models and neurological disease
Nucleotide excision repair (NER) is a highly conserved mechanism to remove helix-distorting DNA base damage. A major substrate for NER is DNA damage caused by environmental genotoxins, most notably ultraviolet radiation. Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy are three huma...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2474780/ https://ncbi.nlm.nih.gov/pubmed/18272436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.12.006 |
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