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Detailed close-ups and the big picture of spliceosomes

The spliceosome is the huge macromolecular assembly responsible for the removal of introns from pre-mRNA transcripts. The size and complexity of this dynamic cellular machine dictates that structural analysis of the spliceosome is best served by a combination of techniques. Electron microscopy is pr...

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Detalles Bibliográficos
Autor principal: Jurica, Melissa S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474778/
https://ncbi.nlm.nih.gov/pubmed/18550358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2008.05.005
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