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The Pathogenesis of the Bone Disease of Multiple Myeloma

Multiple myeloma is a fatal hematologic malignancy associated with clonal expansion of malignant plasma cells within the bone marrow and the development of a destructive osteolytic bone disease. The principal cellular mechanisms involved in the development of myeloma bone disease are an increase in...

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Autori principali: Edwards, Claire M., Zhuang, Junling, Mundy, Gregory R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474770/
https://ncbi.nlm.nih.gov/pubmed/18406675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2008.01.027
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