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Non-Canonical Binding Of An Antibody Resembling A Naïve B Cell Receptor Immunoglobin To Hepatitis B Virus Capsids

The hepatitis B virus capsid (core antigen) is able to bind to and activate naïve B cells whereby these become efficient primary antigen-presenting cells for the priming of T cells. We have investigated this interaction by using cryo-electron microscopy, three-dimensional image reconstruction, and m...

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Main Authors: Watts, Norman R., Cardone, Giovanni, Vethanayagam, Joe G., Cheng, Naiqian, Hultgren, Catharina, Stahl, Stephen J., Steven, Alasdair C., Sällberg, Matti, Wingfield, Paul T.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474722/
https://ncbi.nlm.nih.gov/pubmed/18486949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.04.009
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