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Detection of Catalase as a major protein target of the lipid peroxidation product 4-HNE and the lack of its genetic association as a risk factor in SLE

BACKGROUND: Systemic lupus erythematosus (SLE) is a multifactorial disorder characterized by the presence of autoantibodies. We and others have implicated free radical mediated peroxidative damage in the pathogenesis of SLE. Since harmful free radical products are formed during this oxidative proces...

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מידע ביבליוגרפי
Main Authors: D'souza, Anil, Kurien, Biji T, Rodgers, Rosalie, Shenoi, Jaideep, Kurono, Sadamu, Matsumoto, Hiroyuki, Hensley, Kenneth, Nath, Swapan K, Scofield, R Hal
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474584/
https://ncbi.nlm.nih.gov/pubmed/18606005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-9-62
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