Detection of Catalase as a major protein target of the lipid peroxidation product 4-HNE and the lack of its genetic association as a risk factor in SLE

BACKGROUND: Systemic lupus erythematosus (SLE) is a multifactorial disorder characterized by the presence of autoantibodies. We and others have implicated free radical mediated peroxidative damage in the pathogenesis of SLE. Since harmful free radical products are formed during this oxidative proces...

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Main Authors: D'souza, Anil, Kurien, Biji T, Rodgers, Rosalie, Shenoi, Jaideep, Kurono, Sadamu, Matsumoto, Hiroyuki, Hensley, Kenneth, Nath, Swapan K, Scofield, R Hal
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474584/
https://ncbi.nlm.nih.gov/pubmed/18606005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-9-62
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