Autocrine regulation of mda-7/IL-24 mediates cancer-specific apoptosis

A noteworthy aspect of melanoma differentiation-associated gene-7/interleukin-24 (mda-7/IL-24) as a cancer therapeutic is its ability to selectively kill cancer cells without harming normal cells. Intracellular MDA-7/IL-24 protein, generated from an adenovirus expressing mda-7/IL-24 (Ad.mda-7), indu...

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Main Authors: Sauane, Moira, Su, Zao-zhong, Gupta, Pankaj, Lebedeva, Irina V., Dent, Paul, Sarkar, Devanand, Fisher, Paul B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2008
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474541/
https://ncbi.nlm.nih.gov/pubmed/18599461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804089105
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