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Solution structure of the U2 snRNP protein Rds3p reveals a knotted zinc-finger motif

Rds3p, a component of the U2 snRNP subcomplex SF3b, is essential for pre-mRNA splicing and is extremely well conserved in all eukaryotic species. We report here the solution structure of Rds3p, which reveals an unusual knotted fold unrelated to previously known knotted proteins. Rds3p has a triangul...

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Detalhes bibliográficos
Main Authors: van Roon, Anne-Marie M., Loening, Nikolaus M., Obayashi, Eiji, Yang, Ji-Chun, Newman, Andrew J., Hernández, Helena, Nagai, Kiyoshi, Neuhaus, David
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474504/
https://ncbi.nlm.nih.gov/pubmed/18621724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802494105
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