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Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins

The immunosuppressant rapamycin inhibits Tor1p and Tor2p (target of rapamycin proteins), ultimately resulting in cellular responses characteristic of nutrient deprivation through a mechanism involving translational arrest. We measured the immediate transcriptional response of yeast grown in rich med...

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Hlavní autoři: Hardwick, James S., Kuruvilla, Finny G., Tong, Jeffrey K., Shamji, Alykhan F., Schreiber, Stuart L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC24739/
https://ncbi.nlm.nih.gov/pubmed/10611304
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