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Nucleic acid duplexes incorporating a dissociable covalent base pair

We have used molecular modeling techniques to design a dissociable covalently bonded base pair that can replace a Watson-Crick base pair in a nucleic acid with minimal distortion of the structure of the double helix. We introduced this base pair into a potential precursor of a nucleic acid double he...

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Bibliografische gegevens
Hoofdauteurs: Gao, Kui, Orgel, Leslie E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 1999
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC24734/
https://ncbi.nlm.nih.gov/pubmed/10611299
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