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Disruption of the telomerase catalytic subunit gene from Arabidopsis inactivates telomerase and leads to a slow loss of telomeric DNA

Telomerase is an essential enzyme that maintains telomeres on eukaryotic chromosomes. In mammals, telomerase is required for the lifelong proliferative capacity of normal regenerative and reproductive tissues and for sustained growth in a dedifferentiated state. Although the importance of telomeres...

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Detalhes bibliográficos
Main Authors: Fitzgerald, Matthew S., Riha, Karel, Gao, Feng, Ren, Shuxin, McKnight, Thomas D., Shippen, Dorothy E.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24730/
https://ncbi.nlm.nih.gov/pubmed/10611295
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