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Dyskerin Is a Component of the Arabidopsis Telomerase RNP Required for Telomere Maintenance
Dyskerin binds the H/ACA box of human telomerase RNA and is a core telomerase subunit required for RNP biogenesis and enzyme function in vivo. Missense mutations in dyskerin result in dyskeratosis congenita, a complex syndrome characterized by bone marrow failure, telomerase enzyme deficiency, and p...
में बचाया:
| मुख्य लेखकों: | , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Microbiology (ASM)
2008
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268427/ https://ncbi.nlm.nih.gov/pubmed/18212040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01490-07 |
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