Microbial Transformation of Antibiotics: Phosphorylation of Clindamycin by Streptomyces coelicolor Müller

Addition of clindamycin to whole-cell cultures of Streptomyces coelicolor Müller resulted in the loss of in vitro activity against organisms sensitive to clindamycin. Incubation of such culture filtrates with alkaline phosphatase generated a biologically active material identified as clindamycin. Fe...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Coats, John H., Argoudelis, Alexander D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1971
Assuntos:	Physiology and Metabolism
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247086/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5166238/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.108.1.459-464.1971
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