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Mutagenic Action, Loss of Transforming Activity, and Inhibition of Deoxyribonucleic Acid Template Activity In Vitro Caused by Chemical Linkage of Carcinogenic Polycyclic Hydrocarbons to Deoxyribonucleic Acid
In a solvent system of 10(−2)m phosphate buffer (pH 6.8)-ethanol (2:1, v/v) and in an iodine-induced reaction, the polycyclic hydrocarbons [(3)H]3,4-benzpyrene and [(3)H]3,4-BP/[(3)H]9, 10-dimethyl-1,2-benzanthracene (DMBA) can be covalently linked to deoxyribonucleic acid (DNA) at room temperature....
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1971
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC247052/ https://ncbi.nlm.nih.gov/pubmed/5001197 |
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