Tiagabine is neuroprotective in the N171-82Q and R6/2 mouse models of Huntington's disease

Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder characterized by chorea, incoordination, and shortened life-span, and by huntingtin inclusions and neurodegeneration. We previously screened the 1040 FDA-approved compounds from the NINDS compound library and found that a...

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Hlavní autoři: Masuda, Naoki, Peng, Qi, Li, Qing, Jiang, Mali, Liang, Yideng, Wang, Xiaofang, Zhao, Ming, Wang, Wenfei, Ross, Christopher A., Duan, Wenzhen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2468217/
https://ncbi.nlm.nih.gov/pubmed/18395459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2008.01.014
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