Acute leukemia with promyelocytic features in PML/RARα transgenic mice

Acute promyelocytic leukemia (APL) is associated with reciprocal chromosomal translocations involving the retinoic acid receptor α (RARα) locus on chromosome 17. In the majority of cases, RARα translocates and fuses with the promyelocytic leukemia (PML) gene located on chromosome 15. The resulting f...

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Bibliographische Detailangaben
Hauptverfasser: He, Li-Zhen, Tribioli, Carla, Rivi, Roberta, Peruzzi, Daniela, Pelicci, Pier Giuseppe, Soares, Vera, Cattoretti, Giorgio, Pandolfi, Pier Paolo
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences of the USA 1997
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC24673/
https://ncbi.nlm.nih.gov/pubmed/9144232
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