Identification of nitric oxide synthase as a protective locus against tuberculosis

Mutagenesis of the host immune system has helped identify response pathways necessary to combat tuberculosis. Several such pathways may function as activators of a common protective gene: inducible nitric oxide synthase (NOS2). Here we provide direct evidence for this gene controlling primary Mycoba...

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Main Authors: MacMicking, John D., North, Robert J., LaCourse, Ron, Mudgett, John S., Shah, Shrenik K., Nathan, Carl F.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences of the USA 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC24663/
https://ncbi.nlm.nih.gov/pubmed/9144222
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