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Identification of nitric oxide synthase as a protective locus against tuberculosis

Mutagenesis of the host immune system has helped identify response pathways necessary to combat tuberculosis. Several such pathways may function as activators of a common protective gene: inducible nitric oxide synthase (NOS2). Here we provide direct evidence for this gene controlling primary Mycoba...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: MacMicking, John D., North, Robert J., LaCourse, Ron, Mudgett, John S., Shah, Shrenik K., Nathan, Carl F.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24663/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9144222/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.10.5243
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