Methylation of class II transactivator gene promoter IV is not associated with susceptibility to Multiple Sclerosis

BACKGROUND: Multiple sclerosis (MS) is a complex trait in which alleles at or near the class II loci HLA-DRB1 and HLA-DQB1 contribute significantly to genetic risk. The MHC class II transactivator (MHC2TA) is the master controller of expression of class II genes, and methylation of the promoter of t...

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Main Authors: Ramagopalan, Sreeram V, Dyment, David A, Morrison, Katie M, Herrera, Blanca M, DeLuca, Gabriele C, Lincoln, Matthew R, Orton, Sarah M, Handunnetthi, Lahiru, Chao, Michael J, Sadovnick, A Dessa, Ebers, George C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2464579/
https://ncbi.nlm.nih.gov/pubmed/18606010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-9-63
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