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An SV40 VP1-Derived Epitope Recognized by CD8(+) T Cells Is Naturally Processed and Presented by HLA-A*0201 and Cross-Reactive with Human Polyomavirus Determinants

The CD8+T cell responses directed toward the VP1 antigens of human polyomaviruses JC and BK recently were shown to be cross-reactive. Two HLA-A*0201-restricted determinants from each virus have been defined and include JC p100–108 (ILMWEAVTL) and BK p108–116 (LLMWEAVTV) as well as JC p36–44 (SITEVEC...

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Detalhes bibliográficos
Main Authors: Tagaram, Hephzibah Rani S., Watson, Alan M., Lemonnier, Francois A., Staveley-O’Carroll, Kevin, Tevethia, Satvir S., Schell, Todd D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2464359/
https://ncbi.nlm.nih.gov/pubmed/18402997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.02.033
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