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Development of Zero-Link Polymers of Hemoglobin, Which do not Extravasate and do not Induce Pressure Increases upon Infusion

Intramolecular crosslink of hemoglobin tetramers solved the problem of urine elimination and short intravascular retention time of cell free hemoglobin infusion. It also produced a family of crosslinked hemoglobins with P50 between 18 and 30 mmHg. However, it did not solve the problem of MAP increas...

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Hlavní autoři: Bucci, Enrico, Kwansa, Herman, Koehler, Raymond C., Matheson, Barbara
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2464266/
https://ncbi.nlm.nih.gov/pubmed/17364467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10731190600974277
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