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Development of Zero-Link Polymers of Hemoglobin, Which do not Extravasate and do not Induce Pressure Increases upon Infusion

Intramolecular crosslink of hemoglobin tetramers solved the problem of urine elimination and short intravascular retention time of cell free hemoglobin infusion. It also produced a family of crosslinked hemoglobins with P50 between 18 and 30 mmHg. However, it did not solve the problem of MAP increas...

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Detalhes bibliográficos
Main Authors: Bucci, Enrico, Kwansa, Herman, Koehler, Raymond C., Matheson, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2464266/
https://ncbi.nlm.nih.gov/pubmed/17364467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10731190600974277
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