Isolation of a Mutant of Escherichia coli Defective in Cytosine-Specific Deoxyribonucleic Acid Methylase Activity and in Partial Protection of Bacteriophage λ Against Restriction by Cells Containing the N-3 Drug-Resistance Factor

A mutant (designated mec(−)) of Escherichia coli F(+) 100 endo I(−)su(+) r(K)(−)m(K)(+) has been isolated which is defective in cytosine-specific deoxyribonucleic acid (DNA) methylase activity. The DNA of this mutant, as well as the DNA of phages λ and fd propagated in it, is virtually devoid of 5-m...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Hattman, Stanley, Schlagman, Samuel, Cousens, Lawrence
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1973
Assuntos:	Genetics and Molecular Biology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC246359/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4353870/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.115.3.1103-1107.1973
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