Protein binding and signaling properties of RIN1 suggest a unique effector function

Human RIN1 was first characterized as a RAS binding protein based on the properties of its carboxyl-terminal domain. We now show that full-length RIN1 interacts with activated RAS in mammalian cells and defines a minimum region of 434 aa required for efficient RAS binding. RIN1 interacts with the “e...

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Main Authors: Han, Limin, Wong, Derrick, Dhaka, Ajay, Afar, Daniel, White, Michael, Xie, Wielin, Herschman, Harvey, Witte, Owen, Colicelli, John
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences of the USA 1997
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC24612/
https://ncbi.nlm.nih.gov/pubmed/9144171
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