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A σ(32) mutant with a single amino acid change in the highly conserved region 2.2 exhibits reduced core RNA polymerase affinity

σ(32), the product of the rpoH gene in Escherichia coli, provides promoter specificity by interacting with core RNAP. Amino acid sequence alignment of σ(32) with other sigma factors in the σ(70) family has revealed regions of sequence homology. We have investigated the function of the most highly co...

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Autors principals: Joo, Daniel M., Ng, Norman, Calendar, Richard
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC24604/
https://ncbi.nlm.nih.gov/pubmed/9144163
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