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The individual subunits of the glutamate transporter EAAC1 homotrimer function independently of each other
Glutamate transporters are thought to be assembled as trimers of identical subunits that line a central hole, possibly the permeation pathway for anions. Here, we have tested the effect of multimerization on transporter function. To do so, we coexpressed EAAC1(WT) with the mutant transporter EAAC1(R...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2005
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2459315/ https://ncbi.nlm.nih.gov/pubmed/16128593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi050987n |
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