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Association of loss of epithelial syndecan-1 with stage and local metastasis of colorectal adenocarcinomas: An immunohistochemical study of clinically annotated tumors

BACKGROUND: Syndecan-1 is a transmembrane proteoglycan with important roles in cell-cell and cell-extracellular matrix adhesion and as a growth factor co-receptor. Syndecan-1 is highly expressed by normal epithelial cells and loss of expression has been associated with epithelial-mesenchymal transit...

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Detalhes bibliográficos
Main Authors: Hashimoto, Yosuke, Skacel, Marek, Adams, Josephine C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2459187/
https://ncbi.nlm.nih.gov/pubmed/18590537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-185
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