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Prognostic significance of fascin expression in advanced colorectal cancer: an immunohistochemical study of colorectal adenomas and adenocarcinomas

BACKGROUND: Fascin is an actin bundling protein with roles in the formation of cell protrusions and motility of mesenchymal and neuronal cells. Fascin is normally low or absent from epithelia, but is upregulated in several epithelial neoplasms where it may contribute to an invasive phenotype. Here,...

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Detalhes bibliográficos
Main Authors: Hashimoto, Yosuke, Skacel, Marek, Lavery, Ian C, Mukherjee, Abir L, Casey, Graham, Adams, Josephine C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1615879/
https://ncbi.nlm.nih.gov/pubmed/17029629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-241
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