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Evolution of a New Gene Substituting for the leuD Gene of Salmonella typhimurium: Origin and Nature of supQ and newD Mutations

The second specific enzyme in the biosynthesis of leucine, α-isopropylmalate isomerase, is coded for by two genes, leuC and leuD. Leucine auxotrophs carrying mutations in the leuD gene (including deletions of the entire leuD gene) revert to leucine prototrophy by secondary mutations at the locus sup...

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Detalles Bibliográficos
Publicado en:J Bacteriol
Autor Principal: Kemper, Jost
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1974
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245897/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4612005/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.120.3.1176-1185.1974
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