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Evolution of a New Gene Substituting for the leuD Gene of Salmonella typhimurium: Origin and Nature of supQ and newD Mutations
The second specific enzyme in the biosynthesis of leucine, α-isopropylmalate isomerase, is coded for by two genes, leuC and leuD. Leucine auxotrophs carrying mutations in the leuD gene (including deletions of the entire leuD gene) revert to leucine prototrophy by secondary mutations at the locus sup...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
1974
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC245897/ https://ncbi.nlm.nih.gov/pubmed/4612005 |
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