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The Akt kinase: Molecular determinants of oncogenicity

The serine-threonine kinase Akt is a downstream target of phosphoinositide 3-kinase (PI 3-kinase); it is activated by the phosphoinositide 3-phosphate-dependent kinases PDK1 and PDK2. Certain mutated forms of Akt induce oncogenic transformation in chicken embryo fibroblast cultures and hemangiosarco...

詳細記述

保存先:
書誌詳細
主要な著者: Aoki, Masahiro, Batista, Osvaldo, Bellacosa, Alfonso, Tsichlis, Philip, Vogt, Peter K.
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC24556/
https://ncbi.nlm.nih.gov/pubmed/9843996
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