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The paradox of Akt -mTOR interactions

The serine threonine (ser/thr) protein kinase, Akt, is at the central hub of signaling pathways that regulates cell growth, differentiation and survival. The reciprocal relation that exists between the two activating phosphorylation sites of Akt, T308 and S473, and the two mTOR complexes, C1 and C2,...

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Príomhchruthaitheoirí: LAKSHMIPATHI eVADLAKONDA, Abhinandita eDash, Mukesh ePasupuleti, Anil Kumar eKotha, Pallu eReddanna
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Frontiers Media S.A. 2013-06-01
Sraith:Frontiers in Oncology
Ábhair:
Rochtain ar líne:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00165/full
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