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Pharmacokinetics of meropenem (ICI 194,660) and its metabolite (ICI 213,689) in healthy subjects and in patients with renal impairment.

The pharmacokinetics of meropenem (ICI 194,660) and its open-ring metabolite (ICI 213,689) were studied in 6 healthy volunteers and 16 patients with moderate to severe renal impairment after a single intravenous dose of 500 mg given as a 30-min infusion. Concentrations of unchanged meropenem in plas...

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Bibliografski detalji
Glavni autori: Leroy, A, Fillastre, J P, Borsa-Lebas, F, Etienne, I, Humbert, G
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC245547/
https://ncbi.nlm.nih.gov/pubmed/1482147
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