Cell type-specific anti-human immunodeficiency virus type 1 activity of the transactivation inhibitor Ro5-3335.

The drug Ro5-3335 [7-chloro-5-(2-pyrryl)-3H-1,4-benzodiazepin-2(H)-one] inhibits human immunodeficiency virus type 1 (HIV-1) gene expression at the transcriptional level through interference with Tat-mediated transactivation (M.-C. Hsu, A. D. Schutt, M. Holly, L. W. Slice, M. I. Sherman, D. D. Richm...

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Bibliographic Details
Main Authors: Witvrouw, M, Pauwels, R, Vandamme, A M, Schols, D, Reymen, D, Yamamoto, N, Desmyter, J, De Clercq, E
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC245518/
https://ncbi.nlm.nih.gov/pubmed/1282790
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