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Investigation of the early killing of Staphylococcus aureus by daptomycin by using an in vitro pharmacodynamic model.

The purpose of this study was to develop a pharmacodynamic model to describe the dependency of the rate of Staphylococcus aureus killing upon the concentration of daptomycin. A range of free (unbound) daptomycin concentrations ranging from 0.12 to 27 times the MIC were simulated in the peripheral co...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Vance-Bryan, K, Larson, T A, Rotschafer, J C, Toscano, J P
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245499/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1332596/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.10.2334
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