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Investigation of the early killing of Staphylococcus aureus by daptomycin by using an in vitro pharmacodynamic model.

The purpose of this study was to develop a pharmacodynamic model to describe the dependency of the rate of Staphylococcus aureus killing upon the concentration of daptomycin. A range of free (unbound) daptomycin concentrations ranging from 0.12 to 27 times the MIC were simulated in the peripheral co...

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Autori principali: Vance-Bryan, K, Larson, T A, Rotschafer, J C, Toscano, J P
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1992
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC245499/
https://ncbi.nlm.nih.gov/pubmed/1332596
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