Central nervous system targeting of 2',3'-dideoxyinosine via adenosine deaminase-activated 6-halo-dideoxypurine prodrugs.

AIDS dementia complex is a neurologic disorder, characterized by increasingly severe cognitive, behavioral, and motor impairment, which is associated with human immunodeficiency virus (HIV) infection in the central nervous system (CNS). Many of the dideoxynucleosides effective systemically in the tr...

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Bibliografiska uppgifter

I publikationen:	Antimicrob Agents Chemother
Huvudupphov:	Morgan, M E, Chi, S C, Murakami, K, Mitsuya, H, Anderson, B D
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	American Society for Microbiology (ASM) 1992
Ämnen:	Research Article
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245470/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1444295/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.10.2156
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