Molecular basis of tetracycline action: identification of analogs whose primary target is not the bacterial ribosome.

Tetracycline analogs fell into two classes on the basis of their mode of action. Tetracycline, chlortetracycline, minocycline, doxycycline, and 6-demethyl-6-deoxytetracycline inhibited cell-free translation directed by either Escherichia coli or Bacillus subtilis extracts. A second class of analogs...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Rasmussen, B, Noller, H F, Daubresse, G, Oliva, B, Misulovin, Z, Rothstein, D M, Ellestad, G A, Gluzman, Y, Tally, F P, Chopra, I
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245376/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1725100/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.11.2306
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