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Molecular basis of tetracycline action: identification of analogs whose primary target is not the bacterial ribosome.

Tetracycline analogs fell into two classes on the basis of their mode of action. Tetracycline, chlortetracycline, minocycline, doxycycline, and 6-demethyl-6-deoxytetracycline inhibited cell-free translation directed by either Escherichia coli or Bacillus subtilis extracts. A second class of analogs...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Rasmussen, B, Noller, H F, Daubresse, G, Oliva, B, Misulovin, Z, Rothstein, D M, Ellestad, G A, Gluzman, Y, Tally, F P, Chopra, I
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245376/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1725100/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.11.2306
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