Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis

Integrin ανβ3 is found on a subset of tumor blood vessels where it is associated with angiogenesis and malignant tumor growth. We designed an ανβ3-targeted nanoparticle (NP) encapsulating the cytotoxic drug doxorubicin (Dox) for targeted drug delivery to the ανβ3-expressing tumor vasculature. We obs...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Murphy, Eric A., Majeti, Bharat K., Barnes, Leo A., Makale, Milan, Weis, Sara M., Lutu-Fuga, Kimberly, Wrasidlo, Wolfgang, Cheresh, David A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2008
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453735/
https://ncbi.nlm.nih.gov/pubmed/18607000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803728105
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla