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A Src family kinase inhibitor improves survival in experimental acute liver failure associated with elevated cerebral and circulating VEGF levels

BACKGROUND AND AIMS: Acute liver failure (ALF) is frequently complicated by cerebral edema, systemic inflammation and multi-organ dysfunction. Vascular endothelial growth factor (VEGF) may stimulate liver regeneration but can also be pro-inflammatory, activating endothelial cells and increasing perm...

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Detalhes bibliográficos
Main Authors: Aspinall, Richard J., Weis, Sara M., Barnes, Leo, Lutu-Fuga, Kimberly, Bylund, David J., Pockros, Paul J., Cheresh, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337519/
https://ncbi.nlm.nih.gov/pubmed/21745297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1478-3231.2011.02554.x
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