Dependence of antibody-mediated presentation of antigen on FcRn

The neonatal Fc receptor for IgG (FcRn) is a distant member of the MHC class I protein family. It binds IgG and albumin in a pH-dependent manner and protects these from catabolism by diverting them from a degradative fate in lysosomes. In addition, FcRn-mediated IgG transport across epithelial barri...

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Main Authors: Qiao, Shuo-Wang, Kobayashi, Kanna, Johansen, Finn-Eirik, Sollid, Ludvig M., Andersen, Jan Terje, Milford, Edgar, Roopenian, Derry C., Lencer, Wayne I., Blumberg, Richard S.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453734/
https://ncbi.nlm.nih.gov/pubmed/18599440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801717105
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