Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in vivo

Emerging evidence suggests that myocyte enhancer factor 2 (MEF2) transcription factors act as effectors of neurogenesis in the brain, with MEF2C the predominant isoform in developing cerebrocortex. Here, we show that conditional knockout of Mef2c in nestin-expressing neural stem/progenitor cells (NS...

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Autori principali: Li, Hao, Radford, Jonathan C., Ragusa, Michael J., Shea, Katherine L., McKercher, Scott R., Zaremba, Jeffrey D., Soussou, Walid, Nie, Zhiguo, Kang, Yeon-Joo, Nakanishi, Nobuki, Okamoto, Shu-ichi, Roberts, Amanda J., Schwarz, John J., Lipton, Stuart A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453715/
https://ncbi.nlm.nih.gov/pubmed/18599437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802876105
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