ATM-Dependent Phosphorylation of MEF2D Promotes Neuronal Survival after DNA Damage

Mutations in the ataxia telangiectasia mutated (ATM) gene, which encodes a kinase critical for the normal DNA damage response, cause the neurodegenerative disorder ataxia-telangiectasia (AT). The substrates of ATM in the brain are poorly understood. Here we demonstrate that ATM phosphorylates and ac...

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Main Authors: Chan, Shing Fai, Sances, Sam, Brill, Laurence M., Okamoto, Shu-ichi, Zaidi, Rameez, McKercher, Scott R., Akhtar, Mohd W., Nakanishi, Nobuki, Lipton, Stuart A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965787/
https://ncbi.nlm.nih.gov/pubmed/24672010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2510-12.2014
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