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Immunoglobulin-Like Transcript 3-Fc Suppresses T-Cell Responses to Allogeneic Human Islet Transplants in hu-NOD/SCID Mice

OBJECTIVE—The aim of our study was to explore the immunomodulatory activity of soluble immunoglobulin (Ig)-like transcript (ILT) 3-Fc in pancreatic islet transplantation and to determine its mechanism of action. RESEARCH DESIGN AND METHODS—NOD/SCID mice in which diabetes was induced by streptozotoci...

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Main Authors: Vlad, George, D'Agati, Vivette D., Zhang, Qing-Yin, Liu, Zhuoru, Ho, Eric K., Mohanakumar, Thalachallour, Hardy, Mark A., Cortesini, Raffaello, Suciu-Foca, Nicole
Formato: Artigo
Idioma:Inglês
Publicado: American Diabetes Association 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453624/
https://ncbi.nlm.nih.gov/pubmed/18420485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0054
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