Haplotype Structure of the ENPP1 Gene and Nominal Association of the K121Q Missense Single Nucleotide Polymorphism With Glycemic Traits in the Framingham Heart Study

OBJECTIVE—A recent meta-analysis demonstrated a nominal association of the ectonucleotide pyrophosphatase phosphodiesterase 1 (ENPP1) K→Q missense single nucleotide polymorphism (SNP) at position 121 with type 2 diabetes. We set out to confirm the association of ENPP1 K121Q with hyperglycemia, expan...

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Main Authors: Stolerman, Elliot S., Manning, Alisa K., McAteer, Jarred B., Dupuis, Josée, Fox, Caroline S., Cupples, L. Adrienne, Meigs, James B., Florez, Jose C.
Formato: Artigo
Idioma:Inglês
Publicado: American Diabetes Association 2008
Assuntos:
Genetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453609/
https://ncbi.nlm.nih.gov/pubmed/18426862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0266
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