Anabolic pathway of 6-methoxypurine arabinoside in cells infected with varicella-zoster virus.

6-Methoxypurine arabinoside (ara-M) exhibits potent activity against varicella-zoster virus (VZV) as a result of ara-M's anabolism to the triphosphate of adenine arabinoside (ara-ATP) in VZV-infected cells. The adenosine deaminase inhibitor erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA) enhanced t...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: de Miranda, P, Burnette, T C, Biron, K K, Miller, R L, Averett, D R, Krenitsky, T A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245337/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1662024/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.10.2121
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