6-Methoxypurine arabinoside as a selective and potent inhibitor of varicella-zoster virus.

Seven 6-alkoxypurine arabinosides were synthesized and evaluated for in vitro activity against varicella-zoster virus (VZV). The simplest of the series, 6-methoxypurine arabinoside (ara-M), was the most potent, with 50% inhibitory concentrations ranging from 0.5 to 3 microM against eight strains of...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Averett, D R, Koszalka, G W, Fyfe, J A, Roberts, G B, Purifoy, D J, Krenitsky, T A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245119/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1649571/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.5.851
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