6-Methoxypurine arabinoside as a selective and potent inhibitor of varicella-zoster virus.
Seven 6-alkoxypurine arabinosides were synthesized and evaluated for in vitro activity against varicella-zoster virus (VZV). The simplest of the series, 6-methoxypurine arabinoside (ara-M), was the most potent, with 50% inhibitory concentrations ranging from 0.5 to 3 microM against eight strains of...
Salvato in:
| Pubblicato in: | Antimicrob Agents Chemother |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
1991
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245119/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1649571/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.5.851 |
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